Goldrath_antigen_response
WebStandard name: GOLDRATH_HOMEOSTATIC_PROLIFERATION: Systematic name: MM613: Brief description: Up-regulated in CD8+ T lymphocytes undergoing homeostatic proliferation (HP) versus the naive cells; these genes are not up-regulated versus effector or memory cell population. Full description or abstract: Naive T cells proliferate … http://bio-stage-qa.ucsd.edu/research/faculty/agoldrath.html
Goldrath_antigen_response
Did you know?
WebOct 21, 2024 · From the enriched sets, we found two related to therapy resistance (Massarweh tamoxifen resistance and Creighton endocrine therapy resistance gene sets) and three related to the immune system, such as GOBP immune response, Goldrath antigen response, and CHR6P21, which is a location for genes related to the immune … WebGOLDRATH_ANTIGEN_RESPONSE: Systematic name: MM1255: Brief description: Genes up-regulated at the peak of an antigen response of naive CD8+ [GeneID=925;926] T …
WebApr 10, 2024 · Introduction. In response to T cell receptor (TCR)-mediated recognition of antigens, naive CD8 + T cells rapidly proliferate and acquire cytotoxic and cytokine-producing effector functions to provide protection from infections and tumor growth. Although the majority of effector CD8 + T cells become terminally differentiated and die following … WebMouse Gene Set: GOLDRATH_IMMUNE_MEMORY ... Naive T cells proliferate independently of cognate antigen when introduced into lymphopenic hosts. Lymphopenia-induced proliferation depends on low-affinity MHC/self-peptide complexes and on IL-7. ... The genes induced in response to lymphopenia were largely an attenuated subset of …
WebOct 1, 2003 · We here assessed the influence of IL-15 on antigen-independent expansion and differentiation of human CD8 + T cells. Both naive and primed human T cells divided in response to IL-15. In this process, naive CD8 + T cells successively down-regulated CD45RA and CD28 but maintained CD27 expression. Concomitant with these … WebNov 2, 2015 · ciency and the Goldrath antigen response gene set (Goldrath . ... Cish-de cient T cells mirrored those of genes up-regulated at . the peak of an antigen response …
WebCD8+ T cells are crucial to the control of infection by pathogens that reside in the cytoplasm such as viruses, intracellular bacteria and protozoan parasites. CD8+ T cells recognize …
WebJun 14, 2024 · We identified pathways including Goldrath antigen response (D), Hallmark TNF signaling via NF-κB (E), and Bosco Th1 cytotoxic module (F). Representative … banyan road trailheadWebExternal links: Filtered by similarity ?: Source species: Mus musculus: Contributed by: Jernej Godec (Dana-Farber Cancer Institute) Source platform or identifier namespace: HUMAN_GENE_SYMBOL banyan road boca ratonWebCompendia expression profiles ?: GTEx compendium Human tissue compendium (Novartis) Global Cancer Map (Broad Institute) NCI-60 cell lines (National Cancer Institute): Advanced query: Further investigate these 199 genes : Gene families ?: Categorize these 199 genes by gene family : Show members (show 200 source identifiers mapped to 199 genes) banyan riviera mayaWebSep 29, 2013 · The transcription factor HIF is induced in response to hypoxic stress, TCR activation and cytokines. Goldrath and colleagues show that HIF signaling enhances CTL effector responses and can … banyan robes for saleWeb16 rows · GOLDRATH_ANTIGEN_RESPONSE: Systematic name: M11884: Brief description: Genes up-regulated at the ... banyan robeWebSEKI_INFLAMMATORY_RESPONSE_LPS_DN 23: 16: All SZGR genes in this pathway: GOLDRATH_ANTIGEN_RESPONSE 346: 192: All SZGR genes in this pathway: … banyan root powderWeb15.8.2 Immunotoxic Testing. Testing the T-dependent antigen response has become the main focus of immunotoxicology testing because this response requires the interaction of several different immune cell types and factors, including B lymphocytes, T lymphocytes, antigen presenting cells, and cytokines. Any changes that occur to any component of ... banyan root